Oxidative stress (OS) plays a major role in the neurodegenerative process. Antiapoptotic effects are also involved however, the protective mechanisms exerted by taurine against retinal damage remain to be further investigated. In particular, it has been demonstrated to improve retinal reduced glutathione, malondialdehyde, superoxide dismutase, and catalase activities. The mechanism by which taurine supplementation acts is mainly related to the reduction of oxidative stress. Increasing data indicate that taurine may be effective in slowing down the progression of degenerative retinal diseases, thus suggesting that taurine can be a promising candidate for the prevention or as adjuvant treatment of these diseases. This review will discuss the impact of oxidative stress in retinal neurodegenerative diseases and the potential strategies for avoiding or counteracting oxidative damage in retinal tissues, with a specific focus on taurine. Different approaches using nutraceuticals resulted in protective effects in these disorders.
Indeed, it is well known that oxidative stress is one of the leading causes of retinal degenerative diseases. Retinal disorders are leading causes of blindness and are due to an imbalance between reactive oxygen species and antioxidant scavenger (in favor of pro‐oxidant species) or a disruption of redox signaling and control.
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